Hereditary Cancer Syndrome is hereditary syndrome in which defects in cancer predisposing gene is
inherited to next generation and accounts for 10% of all cancer incidences.¹
If there are defects in cancer disposing genes. Risk of cancer incident is greatly increased and chance of
early onset is also increased.²
Testing for Cancer predisposing genes allows screening of high-risk group to allow for proper medical
management allowing for increased cancer prevention effect and improved treatment.
test for cancer predisposing genes associated with different cancers using
NGS (next generation sequencing) and has been developed with major hospitals in Korea on a national grant.
The tested genes in mainly consists of well document high risk genes
with known management guidelines.³ It is important that whole gene needs to be tested, rather than certain regions,
because cancer inducing variants dispersed over the gene. Unlike some tests which look for variants in certain regions,
checks the whole gene, allowing for more accurate variant detection and thus providing
a better medical diagnostic utility.
is testing the following types of cancer that can be caused by genetic factors :
Kidney & Urinary
SD Genomics performs genetic tests to the requests of medical institutes following the Bioethics and Safety Act. Prior to service request,
understanding the objective of the test, reporting method of the test, and limitations of the test is necessary.
|Required Documents||Test Requirement and Consent form (provided below)|
|TAT||Within 4-6 weeks|
|Report Criteria||Positive : When genetic variants that are likely to cause diseases are found|
|Negative : When genetic variants that are likely to cause diseases are not found|
|Uncertain: When genetic variants are found, but is not possible to be interpreted due to current level of medicine
(When requesting institute has supplied with phenotype information)